The Boss
How about a Nightlife campaign where each of the characters is some kind of bound servant? Some could be traditionally bound (butlers, valets), some could be magically bound (demons), some could bound by circumstance (dj'nn, ghosts), some could be bound by oaths (samurai, corporation men) and all of them have reasons not to want to kill their boss, but, of course, want the opportunity for freedom? It might even be cool to make it a cross-time campaign, where the captors have some kind of cabalistic connection...